CHEMBL3290016


SMILES Cc1c(S(=O)(=O)NCCCCN2CCC(c3noc4cc(F)ccc34)CC2)sc2ccc(F)cc12
InChIKey GCGNPPCFOWHEEJ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 519.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 9.7 9.7 9.7 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 9.15 9.15 9.15 ChEMBL
D2 DRD2 Human Dopamine A pKi 8.72 8.72 8.72 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 8.47 8.47 8.47 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database