CHEMBL312021


SMILES O=C1NCN(c2cccc(Cl)c2)C12CCN(C1Cc3cccc4cccc1c34)CC2
InChIKey UGFJOKRDBOWDIA-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 2
Molecular weight (Da) 417.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 8.9 8.9 8.9 ChEMBL
δ OPRD Human Opioid A pKi 6.8 6.8 6.8 ChEMBL
κ OPRK Human Opioid A pKi 7.3 7.3 7.3 ChEMBL
μ OPRM Human Opioid A pKi 7.7 7.7 7.7 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database