CHEMBL317479


SMILES N[C@H](c1cccc(C(F)(F)F)c1)[C@H]1CCN1C(c1ccccc1)c1ccccc1
InChIKey GAEAFMJGLPCGOT-FGZHOGPDSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 396.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 7.85 7.85 7.85 ChEMBL
δ OPRD Human Opioid A pKi 5.48 5.48 5.48 ChEMBL
κ OPRK Human Opioid A pKi 6.19 6.19 6.19 ChEMBL
μ OPRM Human Opioid A pKi 6.29 6.29 6.29 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database