CHEMBL3342853


SMILES COc1ccccc1N1CCN(CC2COC3(CCN(Cc4ccccc4)CC3)O2)CC1
InChIKey LRLMUKKGKWCSTQ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 437.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1D ADA1D Human Adrenoceptors A pKi 8.33 8.33 8.33 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 8.17 8.17 8.17 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.84 7.84 7.84 ChEMBL
α1B ADA1B Human Adrenoceptors A pKi 7.78 7.78 7.78 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database