CHEMBL103871


SMILES c1ccc(-c2nc(CN3CCN(c4ccccc4)CC3)c[nH]2)cc1
InChIKey PORLBUSMWVWYQB-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 318.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 8.28 8.36 8.44 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.71 6.71 6.71 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.59 6.59 6.59 ChEMBL
D4 DRD4 Human Dopamine A pKi 8.44 8.44 8.44 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database