CHEMBL322873


SMILES CC1CCCN(CCCOc2ccc(-c3ccc(C#N)cc3)cc2)C1
InChIKey MJKGHXXXMDVBEW-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 334.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H3 HRH3 Rat Histamine A pKi 7.58 7.58 7.58 ChEMBL
H2 HRH2 Human Histamine A pKi 4.93 4.93 4.93 ChEMBL
H1 HRH1 Human Histamine A pKi 6.56 6.56 6.56 ChEMBL
H3 HRH3 Human Histamine A pKi 8.77 8.77 8.77 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database