CHEMBL325750
SMILES | O=C1NCN(c2ccccc2)C12CCN(Cc1ccc3nsnc3c1)CC2 |
InChIKey | QHTFQZNDPJWDIE-UHFFFAOYSA-N |
Chemical properties
Hydrogen bond acceptors | 6 |
Hydrogen bond donors | 1 |
Rotatable bonds | 3 |
Molecular weight (Da) | 379.1 |
Drug properties
Molecular type | Small molecule |
Physiological/Surrogate | Surrogate |
Approved drug | No |
Database connections
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
NOP | OPRX | Human | Opioid | A | pIC50 | 6.12 | 6.12 | 6.12 | ChEMBL |
D4 | DRD4 | Human | Dopamine | A | pIC50 | 5.73 | 5.73 | 5.73 | ChEMBL |
D3 | DRD3 | Human | Dopamine | A | pIC50 | 7.54 | 7.54 | 7.54 | ChEMBL |
δ | OPRD | Human | Opioid | A | pIC50 | 5.38 | 5.38 | 5.38 | ChEMBL |
κ | OPRK | Human | Opioid | A | pIC50 | 6.98 | 6.98 | 6.98 | ChEMBL |
μ | OPRM | Human | Opioid | A | pIC50 | 7.53 | 7.56 | 7.6 | ChEMBL |
D2 | DRD2 | Human | Dopamine | A | pIC50 | 6.91 | 6.91 | 6.91 | ChEMBL |