CHEMBL3262088


SMILES CC[C@](O)([C@H]1C[C@@]23CC[C@]1(OC)[C@@H]1Oc4c(O)ccc5c4[C@@]12CCN(CC1CC1)[C@@H]3C5)C(C)(C)C
InChIKey GGVDQPNQFCSAQQ-DKMGXXMGSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 5
Molecular weight (Da) 481.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 6.98 6.98 6.98 ChEMBL
δ OPRD Human Opioid A pKi 9.07 9.07 9.07 ChEMBL
κ OPRK Human Opioid A pKi 9.25 9.25 9.25 ChEMBL
μ OPRM Human Opioid A pKi 8.4 8.4 8.4 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Human Opioid A pEC50 6.74 6.74 6.74 ChEMBL
μ OPRM Human Opioid A pEC50 7.3 7.3 7.3 ChEMBL