CHEMBL3289992


SMILES Cc1cccc(S(=O)(=O)NCCCCN2CCC(c3noc4cc(F)ccc34)CC2)c1
InChIKey BPVLKJSAFIGBKX-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 445.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 8.68 8.68 8.68 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 6.85 6.85 6.85 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 8.82 8.82 8.82 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.77 7.77 7.77 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database