CHEMBL3290001


SMILES O=S(=O)(NCCN1CCC(c2noc3cc(F)ccc23)CC1)c1cccc2ccccc12
InChIKey ZHUCAIBXMOFDCR-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 453.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 9.15 9.15 9.15 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 6.6 6.6 6.6 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 8.89 8.89 8.89 ChEMBL
D2 DRD2 Human Dopamine A pKi 8.04 8.04 8.04 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database