CHEMBL329398


SMILES Oc1nc2c(OCCNCc3ccccc3)cc(Cl)cc2[nH]1
InChIKey YKNNRQLCQGQFRB-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 3
Rotatable bonds 6
Molecular weight (Da) 317.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Rat Dopamine A pKi 8.57 9.09 9.6 ChEMBL
D2 DRD2 Human Dopamine A pKi 8.59 8.59 8.59 ChEMBL
D3 DRD3 Human Dopamine A pKi 8.13 8.13 8.13 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.8 7.8 7.8 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database