CHEMBL3302931


SMILES CN1C(=O)N(CCCCCN2CCN(c3ccccc3F)CC2)C(C)(c2ccccc2)C1=O
InChIKey WYDWWGYMWKKUBI-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 8
Molecular weight (Da) 452.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1A ADA1A Rat Adrenoceptors A pKd 7.32 7.32 7.32 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.91 6.91 6.91 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 4.59 4.59 4.59 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.8 6.8 6.8 ChEMBL
α1B ADA1B Mouse Adrenoceptors A pKd 8.14 8.14 8.14 ChEMBL
α1D ADA1D Rat Adrenoceptors A pKd 8.52 8.52 8.52 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database