CHEMBL3309515


SMILES O=C1CCC2=C([C@@H]3Oc4c(O)ccc5c4[C@@]34CCN(CC3CC3)[C@H](C5)[C@]4(O)C2)N1Cc1ccccc1
InChIKey GTAWNDHRLYTFLJ-UJLGHMMASA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 4
Molecular weight (Da) 484.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 5.89 5.89 5.89 ChEMBL
δ OPRD Human Opioid A pKi 9.44 9.44 9.44 ChEMBL
κ OPRK Human Opioid A pKi 9.82 9.82 9.82 ChEMBL
μ OPRM Human Opioid A pKi 9.74 9.74 9.74 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database