CHEMBL3323653


SMILES O=c1[nH]c2c(O)ccc([C@@H](O)CN[C@H]3CCC[C@H]3C3CCCC3)c2s1
InChIKey LMKMYJGZBLESNG-NOLJZWGESA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 4
Rotatable bonds 5
Molecular weight (Da) 362.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
β2 ADRB2 Human Adrenoceptors A pKi 8.17 8.63 9.1 ChEMBL
β1 ADRB1 Human Adrenoceptors A pKi 7.18 7.67 8.16 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.11 6.12 6.13 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
β2 ADRB2 Guinea pig Adrenoceptors A pIC50 7.64 7.64 7.64 ChEMBL