CHEMBL3616848


SMILES Cc1nnc(S[C@@H]2C[C@@](N)(C(=O)O)[C@@H]3[C@@H](C(=O)O)[C@H]23)[nH]1
InChIKey ZBBCOPQWFRZNNR-YZKWPGIPSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 4
Rotatable bonds 4
Molecular weight (Da) 298.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu2 GRM2 Human Metabotropic glutamate C pKi 6.92 6.92 6.92 ChEMBL
mGlu3 GRM3 Human Metabotropic glutamate C pKi 7.21 7.21 7.21 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu2 GRM2 Human Metabotropic glutamate C pEC50 7.4 7.69 7.98 ChEMBL
mGlu3 GRM3 Human Metabotropic glutamate C pEC50 6.98 6.99 6.99 ChEMBL