4P-PDOT


SMILES CCC(=O)NC1Cc2ccccc2C(C1)c1ccccc1
InChIKey RCYLUNPFECYGDW-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 1
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 279.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MT1 MTR1A Human Melatonin A pKi 6.2 6.7 7.2 Guide to Pharmacology
MT2 MTR1B Human Melatonin A pKi 8.8 9.11 9.41 Guide to Pharmacology
MT2 MTR1B Human Melatonin A pKi 8.82 9.65 10.8 ChEMBL
MT1 MTR1A Human Melatonin A pKi 6.3 6.84 7.23 ChEMBL
MT1 MTR1A Human Melatonin A pKi 6.33 6.33 6.33 PDSP Ki database
MT2 MTR1B Human Melatonin A pKi 8.82 9.91 11.0 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database