CHEMBL3634022


SMILES Cc1ccc2c(n1)CC[C@@H]2NC(=O)COc1cc(C)c2c(C3CC3)nn(C)c2n1
InChIKey FVNQXXWGMZMSAA-KRWDZBQOSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 391.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
OX1 OX1R Human Orexin A pKd 7.27 7.27 7.27 ChEMBL
OX1 OX1R Human Orexin A pKi 6.96 6.96 6.96 ChEMBL
OX2 OX2R Human Orexin A pKd 7.38 7.38 7.38 ChEMBL
OX2 OX2R Human Orexin A pKi 7.66 7.66 7.66 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database