CHEMBL3634821


SMILES Fc1ccc2c(C3CCN(CCCOc4ccc(Cc5nc6ccccc6o5)cc4)CC3)noc2c1
InChIKey DRXDGURYDDKZLG-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 8
Molecular weight (Da) 485.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H1 HRH1 Guinea pig Histamine A pKi 5.5 5.5 5.5 ChEMBL
5-HT2C 5HT2C Rat 5-Hydroxytryptamine A pKi 5.7 5.7 5.7 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 7.67 7.67 7.67 ChEMBL
5-HT7 5HT7R Rat 5-Hydroxytryptamine A pKi 7.72 7.72 7.72 ChEMBL
D2 DRD2 Rat Dopamine A pKi 7.97 7.97 7.97 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database