CHEMBL363581


SMILES CN(C)C[C@@H]1CC2c3ccccc3Sc3ccc(F)cc3[C@H]2O1
InChIKey BSOLCASXROXPRZ-SHZHJNINSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 2
Molecular weight (Da) 329.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.47 7.47 7.47 ChEMBL
H1 HRH1 Human Histamine A pKi 8.92 8.92 8.92 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 7.14 7.14 7.14 ChEMBL
D1 DRD1 Human Dopamine A pKi 7.72 7.72 7.72 ChEMBL
D3 DRD3 Human Dopamine A pKi 8.07 8.07 8.07 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.89 7.89 7.89 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.92 7.92 7.92 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 9.19 9.19 9.19 ChEMBL
α2C ADA2C Human Adrenoceptors A pKi 7.11 7.11 7.11 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database