CHEMBL3403342


SMILES NC(=O)C1CCN(c2c(S(=O)(=O)c3ccccc3)cnc3ccc(Cl)cc23)CC1
InChIKey KOIHILUUMUOCCD-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 429.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 5.46 5.46 5.46 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 5.25 5.25 5.25 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 4.83 4.83 4.83 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 4.73 4.73 4.73 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database