CHEMBL3403345


SMILES Cc1ccc(Cl)cc1N(C)C(=O)c1cn(-c2ccc(F)cc2F)c(=O)c2ccccc12
InChIKey ISQKXWHWYRBJMR-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 3
Molecular weight (Da) 438.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 4.67 4.67 4.67 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 4.95 4.95 4.95 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 4.82 4.82 4.82 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 4.71 4.71 4.71 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database