CHEMBL3423337


SMILES Cn1c(=O)c2c(nc3n(CCCCN4CCN(c5ccc(Cl)cc5)CC4)c(-c4ccccc4)cn23)n(C)c1=O
InChIKey SMRDWSOUDWTDBN-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 9
Hydrogen bond donors 0
Rotatable bonds 7
Molecular weight (Da) 545.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.43 7.43 7.43 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 7.34 7.34 7.34 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 6.35 6.35 6.35 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.64 7.64 7.64 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database