CHEMBL3545812


SMILES NC(N)=NC(=O)c1ccc2c(c1)C1(CCCO1)c1ccccc1-2
InChIKey AWJQWLYQYNSCDJ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 2
Rotatable bonds 1
Molecular weight (Da) 307.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 8.77 8.77 8.77 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 8.29 8.29 8.29 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.82 6.82 6.82 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pIC50 7.8 7.8 7.8 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pIC50 7.26 7.26 7.26 ChEMBL