CHEMBL3581255


SMILES COc1cc2c(cc1OCc1ccccc1)C[C@H]1c3c(cc(OC)c(OC)c3-2)CCN1C
InChIKey VPTMHCAFEUMSIV-NRFANRHFSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 431.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.64 7.64 7.64 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 6.72 6.72 6.72 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.75 6.75 6.75 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.67 6.67 6.67 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.04 7.04 7.04 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database