CHEMBL367045


SMILES CN1CCN(C2=Cn3cccc3Sc3ccccc32)CC1
InChIKey JFLBTRDHDHTNGX-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 1
Molecular weight (Da) 297.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H1 HRH1 Rat Histamine A pKi 8.57 8.57 8.57 ChEMBL
D3 DRD3 Rat Dopamine A pKi 8.08 8.08 8.08 ChEMBL
D1 DRD1 Rat Dopamine A pKi 7.71 7.71 7.71 ChEMBL
M1 ACM1 Rat Acetylcholine (muscarinic) A pKi 5.68 5.68 5.68 ChEMBL
D2 DRD2 Rat Dopamine A pKi 7.76 7.76 7.77 ChEMBL
D3 DRD3 Human Dopamine A pKi 8.08 8.08 8.08 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 8.96 8.96 8.96 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.89 7.89 7.89 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database