CHEMBL363452


SMILES C[C@H](Nc1ccnc(NCCOc2ccc(F)cc2)c1)c1ccccc1
InChIKey RNAQUCCCIRBEBB-INIZCTEOSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 8
Molecular weight (Da) 351.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 9.7 9.7 9.7 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 7.82 7.82 7.82 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.43 6.43 6.43 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database