CHEMBL364270


SMILES CN(C)C[C@@H]1CC2c3ccccc3Oc3ccc(Cl)cc3[C@H]2O1
InChIKey RHPCETHLGGFAQB-SHZHJNINSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 2
Molecular weight (Da) 329.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2C ADA2C Human Adrenoceptors A pKi 6.17 6.17 6.17 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.04 7.04 7.04 ChEMBL
H1 HRH1 Human Histamine A pKi 7.85 7.85 7.85 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 6.52 6.52 6.52 ChEMBL
D1 DRD1 Human Dopamine A pKi 6.6 6.6 6.6 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 8.43 8.43 8.43 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.35 7.35 7.35 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.66 7.66 7.66 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.17 7.17 7.17 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database