CHEMBL365412


SMILES COc1ccccc1N1CCN(C/C=C/CN2C(=O)CCC2=O)CC1
InChIKey LPHGHPDNMQWAKP-SNAWJCMRSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 343.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Rat 5-Hydroxytryptamine A pKi 7.2 7.2 7.2 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 7.54 7.54 7.54 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database