CHEMBL3663460


SMILES CCOc1ncc(Br)cc1C(=O)N1C2CCC1C(COc1ccccn1)C2
InChIKey OEKHYRONKWZPTE-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 431.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
OX1 OX1R Rat Orexin A pKi 7.03 7.03 7.03 ChEMBL
OX1 OX1R Human Orexin A pKi 6.87 6.87 6.87 ChEMBL
OX2 OX2R Human Orexin A pKi 6.27 6.27 6.27 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database