CHEMBL3665682


SMILES Cc1ccc(-c2nn(C)c3nc(OCC(=O)N[C@@H](C)c4ccccc4)cc(C(F)(F)F)c23)cc1
InChIKey CZEJKCUFZXWAKR-INIZCTEOSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 468.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
OX1 OX1R Human Orexin A pKd 6.31 6.31 6.31 ChEMBL
OX2 OX2R Human Orexin A pKd 6.67 6.67 6.67 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database