CHEMBL3669451


SMILES O=C1N(Cc2cccc3cccnc23)CCCC12CCN(c1cnc3ccccc3n1)CC2
InChIKey JSRKOBGHJZTKOT-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 3
Molecular weight (Da) 437.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
OX1 OX1R Human Orexin A pKi 5.75 5.75 5.75 ChEMBL
OX1 OX1R Human Orexin A pKd 5.48 5.48 5.48 ChEMBL
OX2 OX2R Human Orexin A pKi 6.67 6.67 6.67 ChEMBL
OX2 OX2R Human Orexin A pKd 6.68 6.68 6.68 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database