CHEMBL3669469


SMILES O=C1N(Cc2c[nH]c3ccccc23)CCCC12CCN(c1cnc3ccccc3c1)CC2
InChIKey FAHIANPLXOTJJI-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 424.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
OX1 OX1R Human Orexin A pKd 5.74 5.74 5.74 ChEMBL
OX1 OX1R Human Orexin A pKi 5.99 5.99 5.99 ChEMBL
OX2 OX2R Human Orexin A pKd 6.83 6.83 6.83 ChEMBL
OX2 OX2R Human Orexin A pKi 7.5 7.5 7.5 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database