CHEMBL3747052


SMILES CC(C)c1ccccc1OCCN1CCC(N(C)S(=O)(=O)c2ccccc2)CC1
InChIKey NHIJPUMRKSHLBI-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 8
Molecular weight (Da) 416.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 8.05 8.05 8.05 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.58 6.58 6.58 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.85 6.85 6.85 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.22 7.22 7.22 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database