CHEMBL375575


SMILES O=C1c2c(C(F)(F)F)ccc(Cl)c2[C@@H]2CNCCN12
InChIKey JYQPQWBAHAQSSY-QMMMGPOBSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 0
Molecular weight (Da) 290.0

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 5.39 5.39 5.39 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 5.96 5.96 5.96 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.83 5.83 5.83 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pEC50 7.46 7.46 7.46 ChEMBL