CHEMBL375642


SMILES CN1CCN2C(=O)c3c(cccc3C(F)(F)F)[C@@H]2C1
InChIKey QSBTVNVZICWCIZ-JTQLQIEISA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 0
Molecular weight (Da) 270.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 5.8 5.8 5.8 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.37 6.37 6.37 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.38 5.38 5.38 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pEC50 6.38 6.38 6.38 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pEC50 6.53 6.53 6.53 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pEC50 6.0 6.0 6.0 ChEMBL