CHEMBL380054


SMILES Fc1ccc(N2CCN(Cc3cn4ccccc4n3)CC2)cc1
InChIKey BIARYCFROFVWEW-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 3
Molecular weight (Da) 310.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2A 5HT2A Pig 5-Hydroxytryptamine A pKi 6.07 6.07 6.07 ChEMBL
D1 DRD1 Pig Dopamine A pKi 5.08 5.08 5.08 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.51 5.51 5.51 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 5.44 5.44 5.44 ChEMBL
D2 DRD2 Human Dopamine A pKi 4.68 4.7 4.72 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.36 7.36 7.36 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database