CHEMBL374562


SMILES Cc1cc2c(c(C(F)(F)F)c1)C(=O)N1CCNC[C@@H]21
InChIKey KLRMJWTUNWLVEF-JTQLQIEISA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 0
Molecular weight (Da) 270.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 6.47 6.47 6.47 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 8.05 8.05 8.05 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.25 6.25 6.25 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pEC50 6.55 6.55 6.55 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pEC50 8.22 8.22 8.22 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pEC50 6.78 6.78 6.78 ChEMBL