CHEMBL3745815


SMILES CN(C1CCN(CCOc2ccccc2-c2ccccc2)CC1)S(=O)(=O)c1ccc(F)cc1
InChIKey PGTJGPUZZYVGHY-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 8
Molecular weight (Da) 468.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 8.3 8.3 8.3 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.16 7.16 7.16 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.52 7.52 7.52 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.27 7.27 7.27 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database