CHEMBL3746079


SMILES CN(C1CCN(CCOc2ccccc2C(C)(C)C)CC1)S(=O)(=O)c1ccc(F)cc1
InChIKey APKDIQSHDGVEMU-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 7
Molecular weight (Da) 448.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.24 7.24 7.24 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.97 5.97 5.97 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 5.04 5.04 5.04 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.49 6.49 6.49 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database