CHEMBL3746493


SMILES Cn1cc(S(=O)(=O)N(CC2CC2)C2CCN(CCOc3ccccc3C(C)(C)C)CC2)cn1
InChIKey HGUWLKIMYDVIHQ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 9
Molecular weight (Da) 474.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.31 7.31 7.31 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.83 5.83 5.83 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 4.75 4.75 4.75 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.64 6.64 6.64 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database