CHEMBL3747003


SMILES CN(C1CCN(CCOc2ccccc2-c2ccccc2)CC1)S(=O)(=O)c1cnn(C)c1
InChIKey VDUFANHTAMLEII-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 8
Molecular weight (Da) 454.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 8.15 8.15 8.15 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.24 7.24 7.24 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.1 7.1 7.1 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.46 7.46 7.46 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database