CHEMBL3747744


SMILES CC(C)c1ccccc1OCCN1CCC(N(CC2CC2)S(=O)(=O)c2ccc(F)cc2)CC1
InChIKey LKXXVFHPJYDIBI-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 10
Molecular weight (Da) 474.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.55 7.55 7.55 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.38 6.38 6.38 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.6 6.6 6.6 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.7 7.7 7.7 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database