CHEMBL3769441


SMILES COc1cccc(N2CCN(CC(O)CN3C(=O)NC(C)(c4ccc(F)cc4)C3=O)CC2)c1
InChIKey MOEWVEFEDPVMRY-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 7
Molecular weight (Da) 456.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.05 7.05 7.05 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 5.53 5.53 5.53 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.29 5.29 5.29 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pIC50 5.23 5.23 5.23 ChEMBL