CHEMBL3910730


SMILES N#Cc1ccc(CNC(=O)CCCCCN2CCN(c3ccc(F)cc3-c3ccc(C#N)cc3)CC2)cc1
InChIKey AYKZPDMOUBNSMP-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 10
Molecular weight (Da) 509.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.57 7.57 7.57 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 6.03 6.03 6.03 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.86 5.86 5.86 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 5.54 5.54 5.54 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database