CHEMBL3913100


SMILES N#Cc1ccc(CNC(=O)CCOCCN2CCN(c3cccnc3-c3ccccc3)CC2)cc1
InChIKey QOWZCKYSXVTLKA-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 10
Molecular weight (Da) 469.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.06 7.06 7.06 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 5.46 5.46 5.46 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 5.42 5.42 5.42 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.36 5.36 5.36 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database