CHEMBL377612


SMILES CC(=O)N[C@@H](CCCCN(C)C)C(=O)N1CCN(C(=O)C(C)(C)NS(=O)(=O)c2ccc(Cl)c(COc3cccc4ccc(C)nc34)c2Cl)CC1
InChIKey PQSMJBIIJKMKNI-NDEPHWFRSA-N

Chemical properties

Hydrogen bond acceptors 8
Hydrogen bond donors 2
Rotatable bonds 14
Molecular weight (Da) 748.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
B2 BKRB2 Human Bradykinin A pKi 8.0 8.0 8.0 ChEMBL
B2 BKRB2 Human Bradykinin A pKd 7.7 7.7 7.7 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database