CHEMBL378753


SMILES C=CCN1CCC23c4c5ccc(O)c4O[C@@H]2/C(=N/NC(=O)c2ccccc2)CCC3(O)C1C5
InChIKey AKXCFAYOTIEFOH-SOJWNWKASA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 3
Rotatable bonds 4
Molecular weight (Da) 445.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Guinea pig Opioid A pKi 9.52 9.52 9.52 ChEMBL
δ OPRD Human Opioid A pKi 8.85 8.85 8.85 ChEMBL
κ OPRK Guinea pig Opioid A pKi 9.4 9.4 9.4 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database