CHEMBL3819714


SMILES O=C(CCCCN1C2CCC1CC(O)(c1ccc(Cl)cc1)C2)c1nc2ccccc2s1
InChIKey SGGMEYGWAJEGIP-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 454.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.1 7.1 7.1 ChEMBL
H1 HRH1 Human Histamine A pKi 5.99 5.99 5.99 ChEMBL
D4 DRD4 Human Dopamine A pKi 6.29 6.29 6.29 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 6.12 6.12 6.12 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.79 7.79 7.8 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.74 6.75 6.75 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database