CHEMBL1091105


SMILES COc1cc(OC2CCC(C)(C)CC2)c(F)cc1CNC(=O)[C@@H]1CCCN1
InChIKey FGJOAGVKQWXJAD-KRWDZBQOSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 6
Molecular weight (Da) 378.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 5.41 5.41 5.41 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 9.05 9.05 9.05 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.89 7.89 7.89 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pEC50 8.64 8.64 8.64 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pEC50 6.36 6.36 6.36 ChEMBL