CHEMBL385577


SMILES COc1c(Cl)ccc2c1C(=O)N1CCNC[C@@H]21
InChIKey JGMDYLOFCDBBNK-VIFPVBQESA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 1
Molecular weight (Da) 252.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 7.07 7.07 7.07 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.75 6.75 6.75 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.09 6.09 6.09 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pEC50 7.55 7.55 7.55 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pEC50 7.92 7.92 7.92 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pEC50 6.06 6.06 6.06 ChEMBL